Promoter Hypermethylation of LATS2 Gene in Oral Squamous Cell Carcinoma (OSCC) Among North Indian Population.
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چکیده
منابع مشابه
Promoter Hypermethylation of FHIT and P14 Genes in OSCC Patients among North Indian Population
Cancer is the leading cause for death worldwide causing millions of death. Oral squamous cell carcinoma (OSCC) is one the leading cancers causing mortality across the world. Major cause for oral cancer is the smoking, chewing of tobacco and alcohol consumption. It has been found that epigenetic changes are also responsible for the oral cancer. These are caused due to environmental and dietary f...
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MicroRNAs (miRNAs) are small, noncoding RNAs which regulate cell differentiation, proliferation, development, cell cycle, and apoptosis. Expression profiling of miRNAs has been performed and the data show that some miRNAs are upregulated or downregulated in cancer. Several studies suggest that the expression profiles of miRNAs are associated with clinical outcomes. However, the set of miRNAs wi...
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Introduction: The changes in the level of SEPT9 gene promoter methylation can contribute to the formation of esophageal squamous cell carcinoma. The aim of this study was to evaluate the level of changes in the level of SEPT9 gene promoter methylation in the esophageal squamous cell carcinoma. Methods: In the present case-control study, we collected 75 paraffin blocks of esophageal cancer tiss...
متن کاملPromoter hypermethylation of RASSF1A in esophageal squamous cell carcinoma.
PURPOSE The RAS association domain family 1A (RASSF1A) gene, a candidate tumor suppressor gene, is frequently inactivated by hypermethylation of its promoter region in several human cancers. The aim of this study was to evaluate the promoter methylation status of the RASSF1A in esophageal squamous cell carcinoma. EXPERIMENTAL DESIGN We analyzed the methylation status of RASSF1A promoter by me...
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OBJECTIVE To determine the changes in smoking habit among patients with oral squamous cell carcinoma (OSCC) diagnosed and treated in the Service of Stomatology (Valencia University General Hospital. Valencia, Spain). MATERIAL AND METHODS The study involved 123 patients with a history of OSCC interviewed by telephone on their smoking habits at the time of the diagnosis and modifications in hab...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Cancer Prevention
سال: 2020
ISSN: 2476-762X
DOI: 10.31557/apjcp.2020.21.5.1283